Related references
Note: Only part of the references are listed.Allosteric modulation of 42*nicotinic acetylcholine receptors: Desformylflustrabromine potentiates antiallodynic response of nicotine in a mouse model of neuropathic pain
D. Bagdas et al.
EUROPEAN JOURNAL OF PAIN (2018)
Reversal of Nicotine Withdrawal Signs Through Positive Allosteric Modulation of α4ß2 Nicotinic Acetylcholine Receptors in Male Mice
Ayman K. Hamouda et al.
NICOTINE & TOBACCO RESEARCH (2018)
Orthosteric and allosteric potentiation of heteromeric neuronal nicotinic acetylcholine receptors
Jingyi Wang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Role of the Cys Loop and Transmembrane Domain in the Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors
Constanza Alcaino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Unraveling amino acid residues critical for allosteric potentiation of (α4)3(β2) 2-type nicotinic acetylcholine receptor responses
Ze-Jun Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
The (α4)3(β2)2 Stoichiometry of the Nicotinic Acetylcholine Receptor Predominates in the Rat Motor Cortex
Kristen E. DeDominicis et al.
MOLECULAR PHARMACOLOGY (2017)
X-ray structure of the human α4β2 nicotinic receptor
Claudio L. Morales-Perez et al.
NATURE (2016)
Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)3(β2)2 nAChR-Selective Positive Allosteric Modulator
Ayman K. Hamouda et al.
MOLECULAR PHARMACOLOGY (2016)
The role of alpha5 nicotinic acetylcholine receptors in mouse models of chronic inflammatory and neuropathic pain
Deniz Bagdas et al.
BIOCHEMICAL PHARMACOLOGY (2015)
Pro-cognitive activity in rats of 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the 7 nicotinic acetylcholine receptor
A. Potasiewicz et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation
Tasnim S. Mohamed et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2015)
Desformylflustrabromine Modulates α4β2 Neuronal Nicotinic Acetylcholine Receptor High- and Low-Sensitivity Isoforms at Allosteric Clefts Containing the β2 Subunit
Maegan M. Weltzin et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Desformylflustrabromine (dFBr) and [3H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor
Ayman K. Hamouda et al.
MOLECULAR PHARMACOLOGY (2015)
The therapeutic promise of positive allosteric modulation of nicotinic receptors
Victor V. Uteshev
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
Structural and Functional Studies of the Modulator NS9283 Reveal Agonist-like Mechanism of Action at α4β2 Nicotinic Acetylcholine Receptors
Jeppe A. Olsen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Non-equivalent Ligand Selectivity of Agonist Sites in (α4β2)2α4 Nicotinic Acetylcholine Receptors A KEY DETERMINANT OF AGONIST EFFICACY
Simone Mazzaferro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Physostigmine and Galanthamine Bind in the Presence of Agonist at the Canonical and Noncanonical Subunit Interfaces of a Nicotinic Acetylcholine Receptor
Ayman K. Hamouda et al.
JOURNAL OF NEUROSCIENCE (2013)
Positive allosteric modulation of α4β2 nicotinic acetylcholine receptors as a new approach to smoking reduction: evidence from a rat model of nicotine self-administration
Xiu Liu
PSYCHOPHARMACOLOGY (2013)
Augmentation of cognitive function by NS9283, a stoichiometry-dependent positive allosteric modulator of α2- and α4-containing nicotinic acetylcholine receptors
D. B. Timmermann et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations
Dustin K. Williams et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Additional Acetylcholine (ACh) Binding Site at α4/α4 Interface of (α4β2)2α4 Nicotinic Receptor Influences Agonist Sensitivity
Simone Mazzaferro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Unraveling the High- and Low-Sensitivity Agonist Responses of Nicotinic Acetylcholine Receptors
Kasper Harpsoe et al.
JOURNAL OF NEUROSCIENCE (2011)
Pharmacological Characterization of the Allosteric Modulator Desformylflustrabromine and Its Interaction with α4β2 Neuronal Nicotinic Acetylcholine Receptor Orthosteric Ligands
Maegan M. Weltzin et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Structural and functional diversity of native brain neuronal nicotinic receptors
Cecilia Gotti et al.
BIOCHEMICAL PHARMACOLOGY (2009)
The Positive Allosteric Modulator Morantel Binds at Noncanonical Subunit Interfaces of Neuronal Nicotinic Acetylcholine Receptors
Seungmae Seo et al.
JOURNAL OF NEUROSCIENCE (2009)
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
Antoine Taly et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
The antinociceptive response to nicotinic agonists in a mouse model of postoperative pain
Thomas J. Rowley et al.
ANESTHESIA AND ANALGESIA (2008)
Identification of binding sites in the nicotinic acetylcholine receptor for TDBzl-etomidate, a photoreactive positive allosteric effector
Selvanayagam Nirthanan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Potentiation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site
Gareth T. Young et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Allosteric modulation of nicotinic acetylcholine receptors
Daniel Bertrand et al.
BIOCHEMICAL PHARMACOLOGY (2007)
An allosteric modulator of the α7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo
Daniel B. Timmermann et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Synthesis of desformylflustrabromine and its evaluation as an α4β2 and α7 nACh receptor modulator
Jin-Sung Kim et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms
G. Mudo et al.
JOURNAL OF NEURAL TRANSMISSION (2007)
Identification and pharmacological profile of a new class of selective nicotinic acetylcholine receptor potentiators
Lisa M. Broad et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
α4β2 nicotinic receptors with high and low acetylcholine sensitivity:: Pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine
Mirko Moroni et al.
MOLECULAR PHARMACOLOGY (2006)
Potentiation of human α4β2 neuronal nicotinic receptors by a Flustra foliacea metabolite
F Sala et al.
NEUROSCIENCE LETTERS (2005)
Improved protein-ligand docking using GOLD
ML Verdonk et al.
PROTEINS-STRUCTURE FUNCTION AND GENETICS (2003)
Share Paper
