4.0 Article

Very-low-dose continuous drip infusion of landiolol hydrochloride for postoperative atrial tachyarrhythmia in patients with poor left ventricular function

Journal

GENERAL THORACIC AND CARDIOVASCULAR SURGERY
Volume 60, Issue 6, Pages 386-390

Publisher

SPRINGER JAPAN KK
DOI: 10.1007/s11748-012-0011-9

Keywords

Landiolol; Left ventricular dysfunction; Atrial arrhythmia; Postoperative complications

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Three patients with poor left ventricular function (left ventricular ejection fraction < 30 %) developed postoperative atrial tachyarrhythmia in intensive care. Case 1 was a 64-year-old man who underwent a modified Bentall procedure and mitral valve annuloplasty. Case 2 was a 63-year-old woman who underwent quintuple coronary artery bypass grafting. Case 3 was a 65-year-old man who underwent mitral valve replacement. Preoperative intraaortic balloon pumping was required in Cases 2 and 3. Excellent heart rate control with no hemodynamic deterioration was achieved in all three cases by very-low-dose continuous drip infusion of landiolol hydrochloride (2-5 mu g/kg/min). Very-low-dose continuous drip infusion of landiolol hydrochloride is a safe and useful alternative for the control of perioperative atrial tachyarrhythmias in patients with poor left ventricular function.

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