Related references
Note: Only part of the references are listed.Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43
Adam K. Walker et al.
ACTA NEUROPATHOLOGICA (2015)
TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways
Laura De Conti et al.
NUCLEIC ACIDS RESEARCH (2015)
Mitochondrial Dysfunction and Decrease in Body Weight of a Transgenic Knock-in Mouse Model for TDP-43
Carola Stribl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
Hyung-Jun Kim et al.
NATURE GENETICS (2014)
Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
Nael H. Alami et al.
NEURON (2014)
The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit
Sabrina L. Spencer et al.
CELL (2013)
Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
Shuo-Chien Ling et al.
NEURON (2013)
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
Eveline S. Arnold et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Requirements for Stress Granule Recruitment of Fused in Sarcoma (FUS) and TAR DNA-binding Protein of 43 kDa (TDP-43)
Eva Bentmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP
Anais Aulas et al.
MOLECULAR NEURODEGENERATION (2012)
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
Clotilde Lagier-Tourenne et al.
NATURE NEUROSCIENCE (2012)
Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks
Yichen Shi et al.
NATURE PROTOCOLS (2012)
Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates
Sarah J. Parker et al.
NEUROCHEMISTRY INTERNATIONAL (2012)
Overexpression of TDP-43 causes partially p53-dependent G2/M arrest and p53-independent cell death in HeLa cells
Kikyo Lee et al.
NEUROSCIENCE LETTERS (2012)
A Modified RMCE-Compatible Rosa26 Locus for the Expression of Transgenes from Exogenous Promoters
Jan S. Tchorz et al.
PLOS ONE (2012)
Homeostatic neurogenesis in the adult hippocampus does not involve amplification of Ascl1high intermediate progenitors
Ebastian Lugert et al.
NATURE COMMUNICATIONS (2012)
TDP-43 regulates its mRNA levels through a negative feedback loop
Youhna M. Ayala et al.
EMBO JOURNAL (2011)
Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes
Chantelle F. Sephton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
TDP-43-induced Death Is Associated with Altered Regulation of BIM and Bcl-xL and Attenuated by Caspase-mediated TDP-43 Cleavage
Hiroaki Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
Lionel M. Igaz et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
Magdalini Polymenidou et al.
NATURE NEUROSCIENCE (2011)
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
James R. Tollervey et al.
NATURE NEUROSCIENCE (2011)
An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity
Weirui Guo et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Death receptor signalling in central nervous system inflammation and demyelination
Conor Mc Guire et al.
TRENDS IN NEUROSCIENCES (2011)
Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus
Michael J. Devine et al.
NATURE COMMUNICATIONS (2011)
TDP-43: A DNA and RNA binding protein with roles in neurodegenerative diseases
Sadaf T. Warraich et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
TDP-43 Is a Developmentally Regulated Protein Essential for Early Embryonic Development
Chantelle F. Sephton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Cytoplasmic Mislocalization of TDP-43 Is Toxic to Neurons and Enhanced by a Mutation Associated with Familial Amyotrophic Lateral Sclerosis
Sami J. Barmada et al.
JOURNAL OF NEUROSCIENCE (2010)
Rethinking ALS: The FUS about TDP-43
Clotilde Lagier-Tourenne et al.
CELL (2009)
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
Iga Wegorzewska et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail - An important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing
E Buratti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
p53 in neuronal apoptosis
C Culmsee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Human, Drosophila, and C-elegans TDP43:: Nucleic acid binding properties and splicing regulatory function
YM Ayala et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Higher order arrangement of the eukaryotic nuclear bodies
IF Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
J Jonkers et al.
NATURE GENETICS (2001)
Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9
E Buratti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping
E Buratti et al.
EMBO JOURNAL (2001)
p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis
LJ Martin
NEUROBIOLOGY OF DISEASE (2000)
Motor neuron cell death in a mouse model of FALS is not mediated by the p53 cell survival regulator
J Prudlo et al.
BRAIN RESEARCH (2000)
Alteration of the Bcl-x/Bax ratio in a transgenic mouse model of amyotrophic lateral sclerosis:: Evidence for the implication of the p53 signaling pathway
JLG de Aguilar et al.
NEUROBIOLOGY OF DISEASE (2000)
Absence of p53: No effect in a transgenic mouse model of familial amyotrophic lateral sclerosis
C Kuntz et al.
EXPERIMENTAL NEUROLOGY (2000)