Journal
RSC ADVANCES
Volume 8, Issue 25, Pages 13879-13890Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ra02099j
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A palladium catalyzed synthesis of N-H phenanthridinones was developed via C-H arylation. The protocol gives phenanthridinones regioselectively by one-pot reaction without deprotection. It exhibits broad substrate scope and affords targets in up to 95% yields. Importantly, it could be applied for the less reactive o-chlorobenzamides.
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