3.8 Proceedings Paper

Synthesis of Gd2O3 nanoparticles for MRI contrast agents

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IOP PUBLISHING LTD
DOI: 10.1088/1742-6596/352/1/012008

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Funding

  1. Precursory Research for Embryonic Science and Technology of the Japan Science and Technology Agency
  2. Takahashi Industry Foundation for Economic Research
  3. Grants-in-Aid for Scientific Research [23656013] Funding Source: KAKEN

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Gd2O3 nanoparticles were synthesized by using our original method for application as MRI contrast agents. The sample diameters were controlled in the range 18-66 nm by adjusting the annealing temperature between 773 and 1273 K in air or in an Ar atmosphere. Magnetization measurements were performed at 300 K, and the effective magnetic moment of each sample was calculated. They showed paramagnetism at 300 K and they had large effective magnetic moment mu(eff) of 7.15-8.05 mu(B). MRI measurements were performed in 0.8 wt% agarose solution, and the Gd2O3 nanoparticles were found to work as effective T-1-shortening MRI contrast agents.

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