4.1 Article

A practical one-pot synthesis of azides directly from alcohols

Journal

JOURNAL OF CHEMICAL SCIENCES
Volume 124, Issue 3, Pages 687-691

Publisher

INDIAN ACAD SCIENCES
DOI: 10.1007/s12039-012-0241-5

Keywords

Alcohol; azide; triphenylphosphine; iodine; irnidazole; chemoselective

Funding

  1. Council of Scientific and Industrial Research (CSIR), New Delhi [01(1992)/05/EMR-II]
  2. Department of Science and Technology (DST), New Delhi [SR/Sl/OC-25/2007]

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Alkyl/benzyl azides can be readily synthesized in excellent yields from their corresponding alcohols by stirring a solution of sodium azide in DMSO with a thoroughly ground equimolecular mixture of triphenylphosphine, iodine and imidazole.

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