4.1 Article

A novel polymeric catalyst for the one-pot synthesis of 2,4,5-triaryl-1H-imidazoles

Journal

JOURNAL OF CHEMICAL SCIENCES
Volume 124, Issue 3, Pages 717-722

Publisher

INDIAN ACAD SCIENCES
DOI: 10.1007/s12039-012-0248-y

Keywords

2,4,5-Trisubstituted imidazoles; solvent-free synthesis; multicomponent reaction; poly(AMPS-co-AA); heterogeneous catalysts

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An efficient synthesis of 2,4,5-trisubstituted imidazoles is achieved by three component cyclocondensation of benzil or benzoin, aldehyde and ammonium acetate by using novel polymeric catalyst [poly(AMPS-co-AA)] under solvent-free conditions. The key advantages of this process are high yields, shorter reaction times, easy work-up, purification of products by non-chromatographic method and the reusability of the catalyst.

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