4.8 Article

Enantioselective Synthesis of Nonracemic Geminal Silylboronates by Pt-Catalyzed Hydrosilylation

Journal

ACS CATALYSIS
Volume 8, Issue 4, Pages 2897-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acscatal.8b00221

Keywords

hydrosilylation; silicon; boron; catalysis; asymmetric

Funding

  1. NIH [GM-59417]
  2. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM059417] Funding Source: NIH RePORTER

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A Pt-catalyzed enantioselective hydrosilylation of alkenylboronates is described. This reaction occurs with high regio- and enantioselectivity, providing a convenient route to chiral nonracemic geminal silylboronates. These compounds are useful reagents in stereoselective synthesis.

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