Journal
ACS CATALYSIS
Volume 8, Issue 4, Pages 3650-3654Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.8b00626
Keywords
allenes; asymmetric catalysis; enynes; homogeneous catalysis; hydroboration
Categories
Funding
- Nankai University College of Chemistry
- TSRI
- Pfizer, Inc.
- Bristol-Myers Squibb
- National Institutes of Health [1R35GM125052]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R35GM125052] Funding Source: NIH RePORTER
Ask authors/readers for more resources
A method to achieve enantioselective 1,4-hydroboration of terminal and internal enynes to access allenyl boronates under CuH catalysis is described. The reaction typically proceeds in a highly stereoselective manner and tolerates an array of synthetically useful functional groups. The utility of the enantioenriched allenyl boronate products is demonstrated through several representative downstream derivatizations.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available