4.8 Article

A secondary RET mutation in the activation loop conferring resistance to vandetanib

Related references

Note: Only part of the references are listed.
Article Cell Biology

Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors

Dennis Plenker et al.

SCIENCE TRANSLATIONAL MEDICINE (2017)

Article Chemistry, Medicinal

The Effect of Conformational Flexibility on Binding Free Energy Estimation between Kinases and Their Inhibitors

Mitsugu Araki et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2016)

Editorial Material Medicine, General & Internal

Non-Small Cell Lung Cancer and Precision Medicine A Model for the Incorporation of Genomic Features Into Clinical Trial Design

Boris Pasche et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)

Article Oncology

Molecular Mechanisms Underlying Oncogenic RET Fusion in Lung Adenocarcinoma

Tatsuji Mizukami et al.

JOURNAL OF THORACIC ONCOLOGY (2014)

Article Chemistry, Medicinal

Bioisosteres and Scaffold Hopping in Medicinal Chemistry

Nathan Brown

MOLECULAR INFORMATICS (2014)

Review Oncology

Acquired resistance to TKIs in solid tumours: learning from lung cancer

D. Ross Camidge et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2014)

Review Oncology

RET revisited: expanding the oncogenic portfolio

Lois M. Mulligan

NATURE REVIEWS CANCER (2014)

Article Multidisciplinary Sciences

Effects of oncogenic mutations on the conformational free-energy landscape of EGFR kinase

Ludovico Sutto et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Oncology

Tyrosine kinase gene rearrangements in epithelial malignancies

Alice T. Shaw et al.

NATURE REVIEWS CANCER (2013)

Article Biochemistry & Molecular Biology

KIF5B-RET fusions in lung adenocarcinoma

Takashi Kohno et al.

NATURE MEDICINE (2012)

Article Physics, Fluids & Plasmas

Perturbation analyses of intermolecular interactions

Yohei M. Koyama et al.

PHYSICAL REVIEW E (2011)

Article Biochemical Research Methods

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Article Medicine, General & Internal

EML4-ALK Mutations in Lung Cancer That Confer Resistance to ALK Inhibitors

Young Lim Choi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Physics, Fluids & Plasmas

Massively parallel computation of absolute binding free energy with well-equilibrated states

Hideaki Fujitani et al.

PHYSICAL REVIEW E (2009)

Article Chemistry, Medicinal

ASEDock-docking based on alpha spheres and excluded volumes

Junichi Goto et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2008)

Article Chemistry, Physical

GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation

Berk Hess et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2008)

Article Multidisciplinary Sciences

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

Cai-Hong Yun et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Chemistry, Physical

Canonical sampling through velocity rescaling

Giovanni Bussi et al.

JOURNAL OF CHEMICAL PHYSICS (2007)

Article Biochemistry & Molecular Biology

Structure and chemical inhibition of the RET tyrosine kinase domain

Phillip P. Knowles et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Chemistry, Multidisciplinary

Development and testing of a general amber force field

JM Wang et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Article Chemistry, Multidisciplinary

Development of polyphosphate parameters for use with the AMBER force field

KL Meagher et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

The protein kinase complement of the human genome

G Manning et al.

SCIENCE (2002)