Journal
NATURE COMMUNICATIONS
Volume 9, Issue -, Pages -Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41467-017-02791-8
Keywords
-
Categories
Funding
- NIMH [R37MH087027]
- ONR MURI [N00014-16-12832]
- Picower JFDP Fellowship
- NATIONAL INSTITUTE OF MENTAL HEALTH [R37MH087027] Funding Source: NIH RePORTER
Ask authors/readers for more resources
Working memory (WM) activity is not as stationary or sustained as previously thought. There are brief bursts of gamma (similar to 50-120 Hz) and beta (similar to 20-35 Hz) oscillations, the former linked to stimulus information in spiking. We examined these dynamics in relation to readout and control mechanisms of WM. Monkeys held sequences of two objects in WM to match to subsequent sequences. Changes in beta and gamma bursting suggested their distinct roles. In anticipation of having to use an object for the match decision, there was an increase in gamma and spiking information about that object and reduced beta bursting. This readout signal was only seen before relevant test objects, and was related to premotor activity. When the objects were no longer needed, beta increased and gamma decreased together with object spiking information. Deviations from these dynamics predicted behavioral errors. Thus, beta could regulate gamma and the information in WM.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available