Related references
Note: Only part of the references are listed.RNA phase transitions in repeat expansion disorders
Ankur Jain et al.
NATURE (2017)
Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome
Chantal Sellier et al.
NEURON (2017)
RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2
Tao Zu et al.
NEURON (2017)
Regulation of mRNA Translation in Neurons-A Matter of Life and Death
Mridu Kapur et al.
NEURON (2017)
Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31
Taro Ishiguro et al.
NEURON (2017)
Human DDX21 binds and unwinds RNA guanine quadruplexes
Ewan K. S. McRae et al.
NUCLEIC ACIDS RESEARCH (2017)
An Ancient Pseudoknot in TNF-α Pre-mRNA Activates PKR, Inducing eIF2α Phosphorylation that Potently Enhances Splicing
Lise Sarah Namer et al.
CELL REPORTS (2017)
The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD
Brian D. Freibaum et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
New developments in RAN translation: insights from multiple diseases
John Douglas Cleary et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2017)
Neurodegeneration in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9orf72 is linked to TDP-43 pathology and not associated with aggregated forms of dipeptide repeat proteins
Y. Davidson et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2016)
There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS
Aaron D. Gitler et al.
BRAIN RESEARCH (2016)
CGG Repeat-Associated Non-AUG Translation Utilizes a Cap-Dependent Scanning Mechanism of Initiation to Produce Toxic Proteins
Michael G. Kearse et al.
MOLECULAR CELL (2016)
Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames
Xue-hai Liang et al.
NATURE BIOTECHNOLOGY (2016)
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs
Jie Jiang et al.
NEURON (2016)
Translational control by 5′-untranslated regions of eukaryotic mRNAs
Alan G. Hinnebusch et al.
SCIENCE (2016)
The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS brains
Erin G. Conlon et al.
ELIFE (2016)
Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD
Michael Niblock et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2016)
Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers
Tania F. Gendron et al.
ACTA NEUROPATHOLOGICA (2015)
Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers
Ian R. A. Mackenzie et al.
ACTA NEUROPATHOLOGICA (2015)
Targeting the translation machinery in cancer
Mamatha Bhat et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
RAN Translation in Huntington Disease
Monica Banez-Coronel et al.
NEURON (2015)
The awesome power of ribosome profiling
Richard Jackson et al.
RNA (2015)
C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
Jeannie Chew et al.
SCIENCE (2015)
The Scanning Mechanism of Eukaryotic Translation Initiation
Alan G. Hinnebusch
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83 (2014)
Initiation of Translation by Cricket Paralysis Virus IRES Requires Its Translocation in the Ribosome
Israel S. Fernandez et al.
CELL (2014)
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
Aaron R. Haeusler et al.
NATURE (2014)
Structural basis for the inhibition of the eukaryotic ribosome
Nicolas Garreau de Loubresse et al.
NATURE (2014)
eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies
Lise Boussemart et al.
NATURE (2014)
A three-dimensional human neural cell culture model of Alzheimer's disease
Se Hoon Choi et al.
NATURE (2014)
Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α
Gonzalo Viana Di Prisco et al.
NATURE NEUROSCIENCE (2014)
Repeat-Associated Non-AUG Translation and Its Impact in Neurodegenerative Disease
Michael G. Kearse et al.
NEUROTHERAPEUTICS (2014)
Stimulation of ribosomal frameshifting by RNA G-quadruplex structures
Chien-Hung Yu et al.
NUCLEIC ACIDS RESEARCH (2014)
G-Quadruplex Structures Formed by Expanded Hexanucleotide Repeat RNA and DNA from the Neurodegenerative Disease-Linked C9orf72 Gene Efficiently Sequester and Activate Heme
Jason C. Grigg et al.
PLOS ONE (2014)
Translation initiation factor eIF4F modifies the dexamethasone response in multiple myeloma
Francis Robert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations
Ian R. Mackenzie et al.
ACTA NEUROPATHOLOGICA (2013)
C9orf72 frontotemporal lobar degeneration is characterised by frequent neuronal sense and antisense RNA foci
Sarah Mizielinska et al.
ACTA NEUROPATHOLOGICA (2013)
Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins
Kohji Mori et al.
ACTA NEUROPATHOLOGICA (2013)
Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS
Tania F. Gendron et al.
ACTA NEUROPATHOLOGICA (2013)
hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations
Kohji Mori et al.
ACTA NEUROPATHOLOGICA (2013)
The Disease-associated r(GGGGCC)n Repeat from the C9orf72 Gene Forms Tract Length-dependent Uni- and Multimolecular RNA G-quadruplex Structures
Kaalak Reddy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
Peter E. A. Ash et al.
NEURON (2013)
RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
Christopher J. Donnelly et al.
NEURON (2013)
CGG Repeat-Associated Translation Mediates Neurodegeneration in Fragile X Tremor Ataxia Syndrome
Peter K. Todd et al.
NEURON (2013)
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
Tao Zu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
Clotilde Lagier-Tourenne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
Kohji Mori et al.
SCIENCE (2013)
Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
Dhruv Sareen et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Gene Expression Regulation by Upstream Open Reading Frames and Human Disease
Cristina Barbosa et al.
PLOS GENETICS (2013)
Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features
Colin J. Mahoney et al.
BRAIN (2012)
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
Elisa Majounie et al.
LANCET NEUROLOGY (2012)
C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes
Pietro Fratta et al.
SCIENTIFIC REPORTS (2012)
G-quadruplexes in RNA biology
Stefania Millevoi et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2012)
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
Nicholas T. Ingolia et al.
CELL (2011)
Cap-Assisted Internal Initiation of Translation of Histone H4
Franck Martin et al.
MOLECULAR CELL (2011)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Alan E. Renton et al.
NEURON (2011)
Non-ATG-initiated translation directed by microsatellite expansions
Tao Zu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The mechanism of eukaryotic translation initiation and principles of its regulation
Richard J. Jackson et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Toward a structural understanding of IRES RNA function
Megan E. Filbin et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)
Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans
Sarah E. Calvo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Exporting RNA from the nucleus to the cytoplasm
Alwin Koehler et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Back to basics:: the untreated rabbit reticulocyte lysate as a competitive system to recapitulate cap/poly(A) synergy and the selective advantage of IRES-driven translation
Ricardo Soto Rifo et al.
NUCLEIC ACIDS RESEARCH (2007)
Translation elongation after assembly ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA
TV Pestova et al.
GENES & DEVELOPMENT (2003)
An upstream open reading frame impedes translation of the huntingtin gene
J Lee et al.
NUCLEIC ACIDS RESEARCH (2002)
Share Paper
