Journal
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
Volume 10, Issue 1, Pages -Publisher
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/cshperspect.a018267
Keywords
-
Categories
Funding
- National Institutes of Health [R01 GM 095977]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM095977] Funding Source: NIH RePORTER
Ask authors/readers for more resources
The actin cytoskeleton-a collection of actin filaments with their accessory and regulatory proteins-is the primary force-generating machinery in the cell. It can produce pushing (protrusive) forces through coordinated polymerization of multiple actin filaments or pulling (contractile) forces through sliding actin filaments along bipolar filaments of myosin II. Both force types are particularly important for whole-cell migration, but they also define and change the cell shape and mechanical properties of the cell surface, drive the intracellular motility and morphogenesis of membrane organelles, and allow cells to form adhesions with each other and with the extracellular matrix.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available