Journal
JOURNAL OF FUNCTIONAL FOODS
Volume 48, Issue -, Pages 27-36Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jff.2018.06.022
Keywords
Rhodiola rosea; Mouse myotubes; Skeletal muscle; Physical exercise; Reactive oxygen species
Categories
Funding
- grants FRA2013 (University of Trieste, Italy)
- Fondazione Beneficentia Stiftung (Liechtenstein)
Ask authors/readers for more resources
In physiological conditions, the response to oxidative stress induced by strenuous physical training, is not always efficient. Furthermore, a weak muscle fiber antioxidant system can contribute to muscle wasting during ageing and pathological conditions. Natural antioxidant supplements could counteract the effects of oxidative stress. An in vitro model of exercise allowed us to mimic intense or moderate exercise by electrically stimulating cultured mouse myotubes with high- and/or low-frequency pulses; the resulting ROS production was then monitored. The herbal supplement Rhodiola rosea aqueous extract was characterized in terms of its polyphenol content and used to test for antioxidant activity against ROS, produced during muscle contraction. Our results showed that Rhodiola rosea extract reduced the oxidative stress produced by muscle contraction and brought values of ROS production back to physiological levels. We suggest that Rhodiola rosea root extract could exert a protective antioxidant role during intense physical exercise.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available