Journal
JOURNAL OF FUNCTIONAL FOODS
Volume 41, Issue -, Pages 55-61Publisher
ELSEVIER
DOI: 10.1016/j.jff.2017.12.041
Keywords
Probiotic; Prebiotic; Clinical trial; Metabolic syndrome; Mousse
Categories
Funding
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2013/04422-7, 2013/07914-8]
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) [1575592, BEX 6602/15-0]
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) [306330/2016-4]
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This study aimed to evaluate the impact of a synbiotic diet mousse containing Lactobacillus acidophilus La-5 and the prebiotics inulin and fructooligosaccharides on anthropometric and blood pressure measurements, biochemical, inflammatory, haematological, and immunological parameters of volunteers with metabolic syndrome (MetS). In a randomized, double-blind, placebo-controlled trial, forty-five volunteers with MetS were assigned into two groups, each receiving 40 g/day of: synbiotic diet mousse (SDM) (n = 23) and placebo diet mousse (PDM) without pro- and prebiotics (n = 22). All the evaluated parameters were measured at the beginning and after 8 weeks of intervention. The daily intake of SDM and PDM led to significant reductions of total cholesterol and HDL-cholesterol, as well as of immunoglobulins (A and M), and interleukin-1 beta in both groups (p < .05). These results suggest that the presence of the probiotic and prebiotic ingredients in the diet mousse did not show any additional effects on the parameters evaluated in volunteers with MetS.
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