Related references
Note: Only part of the references are listed.Endogenous Probes for Drug Transporters: Balancing Vision With Reality
A. D. Rodrigues et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
Identification of Endogenous Biomarkers to Predict the Propensity of Drug Candidates to Cause Hepatic or Renal Transporter-Mediated Drug-Drug Interactions
Xiaoyan Chu et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
2017 White Paper on recent issues in bioanalysis: aren't BMV guidance/guidelines 'Scientific'? (Part 1-LCMS: small molecules, peptides and small molecule biomarkers)
Jan Welink et al.
BIOANALYSIS (2017)
A highly selective and sensitive LC-MS/HRMS assay for quantifying coproporphyrins as organic anion-transporting peptide biomarkers
Ragu Ramanathan et al.
BIOANALYSIS (2017)
Parallelism experiments to evaluate matrix effects, selectivity and sensitivity in ligand-binding assay method development: pros and cons
Jing Tu et al.
BIOANALYSIS (2017)
Pregnancy Increases the Renal Secretion of N1-methylnicotinamide, an Endogenous Probe for Renal Cation Transporters, in Patients Prescribed Metformin
Mackenzie C. Bergagnini-Kolev et al.
DRUG METABOLISM AND DISPOSITION (2017)
The utility of stable isotope labeled (SIL) analogues in the bioanalysis of endogenous compounds by LC-MS applied to the study of bile acids in a metabolomics assay
Joanna J. Zheng et al.
ANALYTICAL BIOCHEMISTRY (2016)
Determination of Nicotinic Acid and Metabolites in Urine, Cosmetics, and Pharmaceuticals by High-Performance Liquid Chromatography with Novel Electrochemical Detection
Lai-Hao Wang
ANALYTICAL LETTERS (2016)
Quantitative analysis of endogenous compounds
Rhishikesh Thakare et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2016)
A targeted metabolomics assay for cardiac metabolism and demonstration using a mouse model of dilated cardiomyopathy
James A. West et al.
METABOLOMICS (2016)
2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV) (Part 1-small molecules, peptides and small molecule biomarkers by LCMS)
Eric Yang et al.
BIOANALYSIS (2016)
A simple, fast, sensitive and robust LCMS/MS bioanalytical assay for evaluating 7α-hydroxy-4-cholesten-3-one biomarker in a clinical program
Long Yuan et al.
BIOANALYSIS (2016)
N1-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin-trimethoprim interaction
Fabian Mueller et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2015)
Simultaneous determination of N1-methylnicotinamide, L-carnitine, and creatinine in human plasma and urine by liquid chromatography with mass spectrometry for assessing the activities of multiple renal cationic transporters
Yuji Nobuoka et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2014)
Accurate weighing and dilution-assisted plasma microsampling (AWADA-PM): an easy-to-implement and rugged strategy
Michael Leonard et al.
BIOANALYSIS (2014)
Emerging Transporters of Clinical Importance: An Update From the International Transporter Consortium
K. M. Hillgren et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)
Applications of high-resolution MS in bioanalysis
Mike-Qingtao Huang et al.
BIOANALYSIS (2013)
Annotation of the Human Adult Urinary Metabolome and Metabolite Identification Using Ultra High Performance Liquid Chromatography Coupled to a Linear Quadrupole Ion Trap-Orbitrap Mass Spectrometer
Aurelie Roux et al.
ANALYTICAL CHEMISTRY (2012)
Prediction of Transporter-Mediated Drug-Drug Interactions Using Endogenous Compounds
M. F. Fromm
CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)
N-Methylnicotinamide Is an Endogenous Probe for Evaluation of Drug-Drug Interactions Involving Multidrug and Toxin Extrusions (MATE1 and MATE2-K)
S. Ito et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)
Renal drug-drug interactions: what we have learned and where we are going
Eve-Irene Lepist et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2012)
Surrogate matrix and surrogate analyte approaches for definitive quantitation of endogenous biomolecules
Barry R. Jones et al.
BIOANALYSIS (2012)
Recommendations on biomarker bioanalytical method validation by GCC
Richard Hougton et al.
BIOANALYSIS (2012)
European Bioanalysis Forum recommendation on method establishment and bioanalysis of biomarkers in support of drug development
Philip Timmerman et al.
BIOANALYSIS (2012)
Transporter-Mediated Drug-Drug Interactions
L. Zhang et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)
It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS
Ragu Ramanathan et al.
JOURNAL OF MASS SPECTROMETRY (2011)
Transporter-mediated drug-drug interactions
Fabian Mueller et al.
PHARMACOGENOMICS (2011)
Direct injection of lipophilic compounds in the organic phase from liquid-liquid extracted plasma samples onto a reversed-phase column
Henrik Nordberg et al.
BIOANALYSIS (2011)
Analysis of polar metabolites by hydrophilic interaction chromatography-MS/MS
Wenying Jian et al.
BIOANALYSIS (2011)
Development of a Hydrophilic Liquid Interaction Chromatography-High-Performance Liquid Chromatography-Tandem Mass Spectrometry Based Stable Isotope Dilution Analysis and Pharmacokinetic Stud Bioactive Pyridines in Human Plasma and Urine after Coffee Consumption
Roman Lang et al.
ANALYTICAL CHEMISTRY (2010)
Simultaneous determination of nicotinic acid and its four metabolites in rat plasma using high performance liquid chromatography with tandem mass spectrometric detection (LC/MS/MS)
Malgorzata Szafarz et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2010)
Recent advances in application of hydrophilic interaction chromatography for quantitative bioanalysis
Wenying Jian et al.
JOURNAL OF SEPARATION SCIENCE (2010)
A bio-analytical hydrophilic interaction LC-MS/MS method for the simultaneous quantification of omeprazole and lansoprazole in human plasma in support of a pharmacokinetic omeprazole study in children
Julie De Smet et al.
JOURNAL OF SEPARATION SCIENCE (2010)
Membrane transporters in drug development
Kathleen M. Giacomini et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Novel MS solutions inspired by MIST
Ragu Ramanathan et al.
BIOANALYSIS (2010)
Challenges in urine bioanalytical assays: overcoming nonspecific binding
Allena Ji Ji et al.
BIOANALYSIS (2010)
Bioanalytical hydrophilic interaction chromatography: recent challenges, solutions and applications
Raymond Naxing Xu et al.
BIOANALYSIS (2009)
NAD+ and vitamin B3:: From metabolism to therapies
Anthony A. Sauve
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Polyspecific organic cation transporters: Structure, function, physiological roles, and biopharmaceutical implications
Hermann Koepsell et al.
PHARMACEUTICAL RESEARCH (2007)
The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations
Hiroshi Omote et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2
Satohiro Masuda et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Fit-for-purpose method development and validation for successful biomarker measurement
JW Lee et al.
PHARMACEUTICAL RESEARCH (2006)
Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants
T Fujita et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2006)
A human transporter protein that mediates the final excretion step for toxic organic cations
M Otsuka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Principles and applications of LC-MS in new drug discovery
WA Korfmacher
DRUG DISCOVERY TODAY (2005)
Quantitation of the niacin metabolites 1-methylnicotinamide and 1-methyl-2-pyridone-5-carboxamide in random spot urine samples, by ion-pairing reverse-phase HPLC with UV detection, and the implications for the use of spot urine samples in the assessment of niacin status
PI Creeke et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2005)
Direct injection of 96-well organic extracts onto a hydrophilic interaction chromatography/tandem mass spectrometry system using a silica stationary phase and an aqueous/organic phase
ND Weng et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2004)
Direct injection of solid-phase extraction eluents onto silica columns for the analysis of polar compounds isoniazid and cetirizine in plasma using hydrophilic interaction chromatography with tandem mass spectrometry
AC Li et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2004)
Diurnal variations in human urinary excretion of nicotinamide catabolites: effects of stress on the metabolism of nicotinamide
H Okamoto et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2003)
Validation of an HPLC method for the determination of urinary and plasma levels of N-1-methylnicotinamide, an endogenous marker of renal cationic transport and plasma flow
C Musfeld et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2001)
Share Paper
