Journal
FRONTIERS IN NEURAL CIRCUITS
Volume 12, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fncir.2018.00010
Keywords
superior colliculus; mouse; retinotopic map; electrophysiology; sensorimotor systems
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Funding
- National Eye Institute [NEI R21EYO26758, EY022117]
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The superior colliculus (SC) is a midbrain area where visual, auditory and somatosensory information are integrated to initiate motor commands. The SC plays a central role in visual information processing in the mouse; it receives projections from 85% to 90% of the retinal ganglion cells (RGCs). While the mouse SC has been a long-standing model used to study retinotopic map formation, a number of technological advances in mouse molecular genetic techniques, large-scale physiological recordings and SC-dependent visual behavioral assays have made the mouse an even more ideal model to understand the relationship between circuitry and behavior.
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