Journal
INTERNATIONAL WOUND JOURNAL
Volume 15, Issue 6, Pages 909-913Publisher
WILEY
DOI: 10.1111/iwj.12943
Keywords
arsenic; immunoblot; laser scanning confocal microscopy; mucous membrane pemphigoid
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Funding
- National Center of Science, Poland [2 P05B 065 30]
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Mucous membrane pemphigoid (MMP) is a group of chronic autoimmune sub-epithelial blistering disorders, which mostly affect the oral mucosa and the conjunctiva. MMP is very diverse in terms of both the clinical and immunological features (IgG and IgA autoantibodies may react with different antigens). MMP can be induced by infections and medication, including ophthalmologic medication, which may lead to the development of eye lesions. In contrast, a vegetating variant of MMP is extremely rare. Here, we report an MMP case that demonstrated unusual clinical features, that is, pyogenic granulomas on the conjunctivae and extensive vegetating erosions on the skin of intertriginous regions. All these lesions were considered to be induced by unconventional medication containing arsenic.
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