4.8 Article

Highly sensitive and stable zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT) glucose biosensor

Journal

CHEMICAL SCIENCE
Volume 9, Issue 9, Pages 2540-2546

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7sc05104b

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Funding

  1. US National Science Foundation [DMR-1454837, DMR-1206923]
  2. National Natural Science Foundation of China [NSFC-51528301]
  3. Direct For Mathematical & Physical Scien
  4. Division Of Materials Research [1741935] Funding Source: National Science Foundation

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A zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT)-based glucose biosensor was fabricated via encapsulating glucose oxidase (GOx) in a one-step electropolymerization method. Integrating conductivity and hydrophilic properties, PSBEDOT provides a great framework for GOx immobilization and stabilization. The anti-fouling, high-sensitivity, and long-term stability properties of PSBEDOT-GOx make it a promising platform for long-term and continuous glucose monitoring.

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