Journal
WIENER KLINISCHE WOCHENSCHRIFT
Volume 130, Issue 17-18, Pages 530-534Publisher
SPRINGER WIEN
DOI: 10.1007/s00508-018-1356-6
Keywords
Helicobacter pylori; Diagnosis; Invasive test; Non-invasive test
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Helicobacter pylori infections represent an important factor in the pathogenesis of chronic gastritis, peptic ulcer, MALT lymphoma and gastric adenocarcinoma. The recently published Maastricht V/Florence consensus report indicated that the urea breath test using 13C urea still remains the best non-invasive test to diagnose H. pylori infections with high sensitivity and specificity. Among the stool antigen tests, the ELISA monoclonal antibody test is a rational option. Effective therapy should be based only on susceptibility testing in regions with documented high clarithromycin resistance (> 15%). Advanced high-resolution endoscopic technologies enable increased diagnostic accuracy for detection of H. pylori infections.
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