Journal
VETERINARY JOURNAL
Volume 233, Issue -, Pages 41-48Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tvjl.2017.12.025
Keywords
African swine fever; Control; Epidemiology; Immune responses; Pathogenesis; Vaccination
Categories
Funding
- Biotechnology and Biological Sciences Research Council (BBSRC) [BB/E/I/00002014, BB/L004267/1, BBS/E/I/00001714, DEFRA SE1515]
- Biotechnology and Biological Sciences Research Council [BBS/E/I/00007030, BBS/E/I/00001714, BBS/E/I/00007037, BB/L004267/1, BBS/E/I/00007031] Funding Source: researchfish
- BBSRC [BBS/E/I/00007037, BBS/E/I/00007030, BB/L004267/1, BBS/E/I/00007031] Funding Source: UKRI
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African swine fever (ASF) recently has spread beyond sub-Saharan Africa to the Trans-Caucasus region, parts of the Russian Federation and Eastern Europe, In this new epidemiological scenario, the disease has similarities, but also important differences, compared to the situation in Africa, including the substantial involvement of wild boar. A better understanding of this new situation will enable better control and prevent further spread of disease. In this article, these different scenarios are compared, and recent information on the pathogenesis of ASF virus strains, the immune response to infection and prospects for developing vaccines is presented. Knowledge gaps and the prospects for future control are discussed. (C) 2018 The Pirbright Institute. Published by Elsevier Ltd.
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