Journal
UROLOGIA INTERNATIONALIS
Volume 100, Issue 3, Pages 263-270Publisher
KARGER
DOI: 10.1159/000486138
Keywords
Urinary tract infection; Cystitis; Pyelonephritis; Diagnosis; Systematic review; Clinical guideline
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Funding
- Leo Pharma
- Astellas
- Monika Kutzner Stiftung
- Pfizer
- Bionorica
- Daiichi Sanchyo
- MerLion
- OM-Pharma
- Rosen Pharma
- Zambon
- Basilea
- Enteris
- Helperby
- Rosen-Pharma
- Akademie der Deutschen Urologen
- CGC Cramer
- Fischerappelt
- Fresenius
- Gilead
- Infectopharm
- MDS
- MedConcept
- MIM-Verlag
- Omega/Abtei
- Pfleger
- Springer-Verlag
- Strathmann Thieme-Verlag
- Uromed
- Achaogen
- AstraZeneca
- Cubist
- Galenus
- MSD
- Pierre Fabre
- Pierelle Research
- Calixa
- DFG
- Europ. Ass. f. Urologie
- Hess. Minist. f. Wirtschaft und Kunst
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Objectives: We aimed to update the 2010 evidence- and consensus-based national clinical guideline on the diagnosis and management of uncomplicated urinary tract infections (UTIs) in adult patients. Materials and Methods: An interdisciplinary group consisting of 17 representatives of 12 medical societies and a patient representative was formed. Systematic literature searches were conducted in MEDLINE, EMBASE, and the Cochrane Library to identify literature published in 2010-2015. Results: We provide 75 recommendations and 68 statements in the updated evidence- and consensus-based national clinical guideline. The diagnostics part covers practical recommendations on cystitis and pyelonephritis for each defined patient group. Clinical examinations, as well as laboratory testing and microbiological pathogen assessment, are addressed. Conclusion: In accordance with the global antibiotic stewardship initiative and considering new insights in scientific research, we updated our German clinical UTI guideline to promote a responsible antibiotic use and to give clear hands-on recommendations for the diagnosis and management of UTIs in adults in Germany for healthcare providers and patients. (c) 2018 S. Karger AG, Basel.
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