4.6 Editorial Material

Atherosclerosis Is an Epigenetic Disease

Journal

TRENDS IN ENDOCRINOLOGY AND METABOLISM
Volume 29, Issue 11, Pages 739-742

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tem.2018.04.007

Keywords

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Funding

  1. National Institutes of Health (NIH) [HL09502, HL114570, HL128363, HL130167]
  2. American Heart Association [17GRNT33660671]

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Atherosclerosis is a chronic inflammatory and lipid-depository disease that eventually leads to acute cardiovascular events. Emerging evidence supports that epigenetic processes such as DNA methylation, histone modification, and noncoding RNAs play an important role in plaque progression and vulnerability, highlighting the therapeutic potential of epigenetic drugs in cardiovascular therapeutics.

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