4.6 Editorial Material

New ADCY3 Variants Dance in Obesity Etiology

Journal

TRENDS IN ENDOCRINOLOGY AND METABOLISM
Volume 29, Issue 6, Pages 361-363

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tem.2018.02.004

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Funding

  1. National Natural Science Foundation of China [91540113, 81570527, 81502631]

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The genetic etiology for obesity-related traits remains elusive. Recent studies link novel ADCY3 variants to obesity and diabetes, and identify an important role of ADCY3-mediated signaling at neuronal primary cilia in the predisposition of obesity. These findings provide new information on obesity etiology and suggest potential anti-obesity therapeutic strategies.

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