Journal
TRENDS IN BIOCHEMICAL SCIENCES
Volume 43, Issue 1, Pages 4-9Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2017.11.001
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Funding
- Canadian Institutes of Health Research
- FRQS
- Ligue Nationale Contre le Cancer (equipe labellisee)
- INCa
- ANR [PLBIO 2016-161, ANR-16-CE11-0032]
- Bell-Bombardier Chair of Excellence - IRCM
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The Rvb1-Rvb2-Tah1-Pih1/pre-foldin-like (R2TP/PFDL) complex is a unique chaperone that provides a platform for the assembly and maturation of many key multiprotein complexes in mammalian cells. Here, we propose to rename R2TP/PFDL as PAQosome (particle for arrangement of quaternary structure) to more accurately represent its unique function.
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