Journal
JOURNAL OF BIOMEDICAL SCIENCE
Volume 19, Issue -, Pages -Publisher
BMC
DOI: 10.1186/1423-0127-19-92
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Funding
- Ministere de l'Enseignement Superieur et de la Recherche
- Institut National de la Sante et de la Recherche Medicale
- Agence Nationale de la Recherche sur le Sida et les Hepatites Virales (ANRS)
- Institut National du Cancer (INCa)
- NIAID
- office of the Director, NIH
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Autophagy is a protein degradative process important for normal cellular metabolism. It is apparently used also by cells to eliminate invading pathogens. Interestingly, many pathogens have learned to subvert the cell's autophagic process. Here, we review the interactions between viruses and cells in regards to cellular autophagy. Using findings from hepatitis B virus and human retroviruses, HIV-1 and HTLV-1, we discuss mechanisms used by viruses to usurp cellular autophagy in ways that benefit viral replication.
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