Journal
TOXIN REVIEWS
Volume 39, Issue 1, Pages 1-13Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/15569543.2018.1474926
Keywords
Reproduction; oxidative stress; antioxidants; pesticides; infertility
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Funding
- CSIR (Council of Scientific and Industrial Research), New Delhi
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Oxidative stress impairs the female reproductive physiology by altering the affectivity of antioxidant defense system in the individual. Several toxicants mainly pesticides alters this defense system producing various lifestyle-related diseases. The imbalance in antioxidant defense system, due to pesticidal toxicity-induced oxidative stress, is found to be associated with reproductive disorders like estrous cycle defects, impaired folliculogenesis, follicular atresia, implantation defects, spontaneous abortions, endometriosis, fetal, and other birth defects, thereby, directly affecting fertility and reproductive physiology of the organism. So, the present review emphasizes upon pesticides-mediated oxidative stress and its influence on female fertility.
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