Visible light mediated aerobic photocatalytic activation of C-H bond by riboflavin tetraacetate and N-hydroxysuccinimide

A green and highly efficient cooperative photocatalytic system which consists of riboflavin tetraacetate (RFT), N-hydroxysuccinimide (NHS) and FeCl3 center dot 6H(2)O has been developed for C-H bond oxygenation with visible light under mild reaction conditions. Compared to the previous procedures about C-H bond activation by using flavins as photocatalyst, we use cheap ferric chloride and NHS instead of expensive scandium triflate or biomimetic non-heme iron complex, further expand the substrate scopes. In addition, a possible radical mechanism for the C-H bond oxygenation in this photocatalytic system is proposed. (C) 2018 Elsevier Ltd. All rights reserved.