4.4 Article

Synthesis of β-heteroaryl carbonyl compounds via direct cross-coupling of allyl alcohols with heteroaryl boronic acids under cooperative bimetallic catalysis

Journal

TETRAHEDRON LETTERS
Volume 59, Issue 14, Pages 1352-1355

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2018.02.021

Keywords

beta-Heteroaryl carbonyl compounds; Allyl alcohols; Heteroaryl boronic acids; Photocatalysis reaction

Funding

  1. Natural Science Foundation of China [21172200, 21702191]

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The eco-friendly cooperative Cu/Pd-catalyzed oxidative Heck reaction of ally! alcohols with heteroaryl boronic acids under air was described. The ready availability of starting materials and the mild reaction conditions made this protocol a safe and operationally convenient strategy for the efficient synthesis of beta-heteroaryl carbonyl compounds. (C) 2018 Published by Elsevier Ltd.

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