Journal
TETRAHEDRON LETTERS
Volume 59, Issue 24, Pages 2372-2375Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2018.05.027
Keywords
Pyrido[1,2-a]benzimidazole; Hydrazone; Bioimaging; Fluorescent probe; Hypochlorite
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Funding
- Natural Science Foundation of China [21602153, 11574009]
- Science Fund of Shandong Province for Excellent Young Scholars [ZR2017JL015]
- Science and Technology Development Plan of Tai'an [2016GX1018]
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A novel fluorophore pyrido[l,2-a]benzimidazole was synthesized and used as a fluorescent probe for hypochlorite based on the oxidation of hydrazine to carboxyl group. The detection limit was measured to be as low as 7.0 nM. The probe can realize fast-detection for hypochlorite within 60 s. Furthermore, it could be used for imaging in living cells. (C)18 Elsevier Ltd. All rights reserved.
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