Journal
TETRAHEDRON LETTERS
Volume 59, Issue 24, Pages 2365-2367Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2018.05.020
Keywords
Tandem azidation; Intramolecular cycloaddition; Regioselective; Triazoles
Categories
Funding
- CSIR, New Delhi
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An efficient one-pot method for the synthesis of substituted 1,2,3-triazole derivatives in excellent yields as single regioisomer is reported. The key transformation involves an atom-efficient tandem azidation, intramolecular [3+2]-cycloaddition and aromatization of acrylate derivatives on treatment with NaN3 in DMF under mild conditions. (C) 2018 Elsevier Ltd. All rights reserved.
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