Journal
TETRAHEDRON LETTERS
Volume 59, Issue 23, Pages 2205-2213Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2018.04.057
Keywords
Alkynes; Enantioselective synthesis; Homogeneous catalysis; Hydrofunctionalization; Transition-metal catalysis
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Funding
- National 1000 Youth Talents Plan
- State Key Laboratory of Elemento-Organic Chemistry at Nankai University
- College of Chemistry at Nankai University
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A significant number of reactions regarding hydrofunctionalization of alkynes have appeared in the literature over the years. This digest focus on the transition-metal catalyzed enantioselective alkyne hydrofunctionalization reactions. Based on the reaction mechanism, these reactions described herein are classified into three types. Strategies, substrate scope, along with mechanisms are highlighting. (C) 2018 Elsevier Ltd. All rights reserved.
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