Journal
TETRAHEDRON
Volume 74, Issue 38, Pages 5340-5350Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2018.04.003
Keywords
Synthetic methodology; Bioactive natural product; Chromone; Xanthone; Cyclopropane
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Funding
- University of Otago
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We report the rapid synthesis of various cycloheptane-fused chromones and an oxepine fused flavone in 5 steps from the corresponding 2-hydroxy acetophenone. Furthermore, we describe the synthesis of xanthones, in moderate to good yield, from 2,3-disubstituted flavones using a Friedel Crafts alkylation strategy. (C) 2018 Elsevier Ltd. All rights reserved.
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