Journal
TETRAHEDRON
Volume 74, Issue 27, Pages 3391-3457Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2018.04.076
Keywords
Multicomponent reaction; Click chemistry; Name reaction; Heterocycles; Knoevenagel reaction; Michael reaction; Diels-Alder reaction; Aldol reaction; Mannich reaction; Ugi reaction; Heck reaction; Huisgen reaction; Suzuki reaction
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In this report, we try to show the importance of incorporation of name reactions in the sequential cascade reaction in which significantly decreasing the number of steps towards an ideal and practical multi-step synthesis of natural products as well showing virtually all the advantages already mentioned for Click Chemistry. In addition, since the chiral inductions are desired for most of these sequential name reactions, their asymmetric catalyzed reactions were also described. (C) 2018 Elsevier Ltd. All rights reserved.
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