Journal
TETRAHEDRON
Volume 74, Issue 38, Pages 5351-5357Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2018.05.066
Keywords
Flow; Photochemistry; Heterocyclic metamorphosis; Quinoline N-oxide; Benz[1,3]oxazepine
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Funding
- Chemical Analysis Facility
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C-H Activation/functionalisation and Flow Photochemical Heterocyclic Metamorphosis (FP-HM) have been combined to synthesize a library of benzo [1,3]oxazepines, a rarely described heterocyclic family. This combined protocol allows a range of arylated products to be made from simple starting materials, and the cheap flow photochemical system has proven effective for rapid synthesis of gram-quantities of benzo [1,3]oxazepines. (C) 2018 Elsevier Ltd. All rights reserved.
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