Journal
TALANTA
Volume 184, Issue -, Pages 356-363Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.talanta.2018.02.105
Keywords
Ambient ionization; Electrospray; Mass spectrometry; Medical swabs; In vivo sampling; Point-of-care testing
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Funding
- Purdue University Center for Cancer Research
- Copan Diagnostics
- Puritan Medical Products
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Medical swabs are used for biofluid and tissue sampling in clinical applications. The use of medical swabs as electrospray ionization probes for direct mass spectrometric analysis is a novel and potentially widely applicable development. Here we discuss ion generation, characterize ionization behavior via microscopic videography and describe some illustrative examples of applications.
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