Journal
TALANTA
Volume 179, Issue -, Pages 601-607Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.talanta.2017.11.066
Keywords
Polymer inclusion membranes; PIM; Electromembrane extraction; Non-steroidal anti-inflammatory drugs; Polar drugs
Categories
Funding
- Direccion General de Investigacion y Gestion del Plan Nacional de I + D + i (Ministerio de Educacion y Ciencia, Spain) [CTM2015-67902-C-1-P]
- University of Sevilla through the V Plan Propio de Investigacion de la Universidad de Sevilla
Ask authors/readers for more resources
The use of polymer inclusion membranes (PIMs) as support of 1-octanol liquid membrane in electromembrane extraction (EME) procedure is proposed. Synthesis of PIMs were optimized to a composition of 29% (w/w) of cellulose triacetate as base polymer and 71% (w/w) of Aliquat (R) 336 as cationic carrier. Flat PIMs of 25 gm thickness and 6 mm diameter were used. EME protocol was implemented for the simultaneous extraction of four non-steroidal anti-inflammatory drugs (NSAIDs) (salicylic acid, ketoprofen, naproxen and ibuprofen) and four highly polar acidic drugs (anthranilic acid, nicotinic acid, amoxicillin and hippuric acid). Posterior HPLC separation of the extracted analytes was developed with diode array detection. Recoveries in the 81-34% range were obtained. EME procedure was applied to human urine samples.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
