4.7 Article

Flow analysis with chemiluminescence detection: Recent advances and applications

Journal

TALANTA
Volume 179, Issue -, Pages 246-270

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.talanta.2017.11.007

Keywords

Flow analysis; CL detection; Sample preparation; Food analysis; Environmental analysis; Pharmaceutical analysis

Funding

  1. St. Petersburg State University [12.42.1462.2015]
  2. Russian Foundation for Basic Research [16-33-60137 mol_a_dk]
  3. Russian Government [MD-6597.2016.3]

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This article highlights the most important developments in flow analysis with chemiluminescence (CL) detection, describing different flow systems that are compatible with CL detection, detector designs, commonly applied CL reactions and approaches to sample treatment. Recent applications of flow analysis with CL detection (focusing on outputs published since 2010) are also presented. Applications are classified by sample matrix, covering foods and beverages, environmental matrices, pharmaceuticals and biological fluids. Comprehensive tables are provided for each area, listing the specific sample matrix, CL reaction used, linear range, limit of detection and sample treatment for each analyte. Finally, recent and emerging trends in the field are also discussed.

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