Journal
TALANTA
Volume 178, Issue -, Pages 663-669Publisher
ELSEVIER
DOI: 10.1016/j.talanta.2017.09.089
Keywords
Chemosensor; Hg2+ ions; Thioacetal; Intramolecular charge transfer
Categories
Funding
- Natural Science Foundation of Shaanxi Province [2016JM2013]
- National Natural Science Foundation of China [21073143]
- NPU Foundation for Graduate Innovation [Z2017208]
Ask authors/readers for more resources
This work reports a facile strategy for the synthesis of water-soluble fluorescent probes Pyrl and Pyr2, which have carboxyl and hydroxyl group in the side chain of thioacetal moiety, respectively. Pyr1-2 exhibit exclusively selective turn-on fluorescence response towards Hg2+ over other cations, based on intramolecular charge transfer (ICT) mechanism. Upon addition of Hg2+, the thioacetal moiety in Pyr1-2 can be converted to aldehyde group, which is confirmed by H-1 NMR titration. The detection limits for Pyr1-2 are less than 1.80 nM in aqueous media, lower than the maximum allowable level of Hg2+ in drinking water by EPA. Moreover, Pyr2 have been successfully used for fluorescence imaging of Hg2+ in living cells, demonstrating potential application in biological science.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available