Synthesis, characterization, in vitro, and in silico studies of 4-(2-hydroxybenzoyl) and 4-(2-hydroxynaphthoyl)-thiabenzene-1-methyl-1-oxides

A variety of 4-(2-hydroxybenzoyl) and 4-(2-hydroxynaphthoyl) thiabenzene-1-methyl-1-oxides have been prepared by the reaction of dimethylsulfoxoniummethylide with 3-formyl-chromones and screened for their anticancer activities on lung cancer cell line by in vitro and in silico studies. [GRAPHICS] .