Journal
SYNTHESIS-STUTTGART
Volume 50, Issue 8, Pages 1601-1609Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0036-1591946
Keywords
isatins; heterocyclization; indoles; C-C bond formation; catalysis
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Isatin derivatives are widely used in organic synthesis, in medicinal chemistry and in the chemistry of materials. This report summarizes modern trends in the synthesis of substituted indolin-2,3-diones covering the literature from 2007 to 2017. Studies on the influence of the structure of substituents in the initial substrates on the formation of the heterocyclic isatin system and the yields of the target compounds are also discussed. 1 Introduction 2 Oxidation of Indole Derivatives 3 Cyclization of o -Aminoacetophenones 4 Cyclization of N -Acylanilines 5 Miscellaneous 6 Conclusion
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