Journal
SURVEY OF OPHTHALMOLOGY
Volume 63, Issue 6, Pages 869-874Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.survophthal.2018.05.003
Keywords
LSCD; limbal cells; amniotic membrane; SLET; transplant
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Funding
- 2017 European Action in Science and Technology EU COST Summer Training School grant [BM1302]
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Simple limbal epithelial transplantation is a recently developed technique for treating limbal stem cell deficiency caused by ocular burns. A small limbal biopsy from the donor eye, usually from the patient's healthy eye, is excised and dissected into multiple pieces. An amniotic membrane is atttached using fibrin glue on the diseased eye after removing the conjunctivalized pannus from the corneal surface. The limbal biopsy pieces are placed onto the amniotic membrane, fixed with fibrin glue, followed by bandaging of the ocular surface with a contact lens. This technique (auto simple limbal epithelial transplantation) offers easier surgical manipulations and economic advantages over other techniques for the treatment of limbal stem cell deficiency. We therefore review simple limbal epithelial transplantation along with recent modifications in the technique and case studies, including challenges and failures. (C) 2018 Elsevier Inc. All rights reserved.
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