Journal
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
Volume 33, Issue 3, Pages 789-793Publisher
SPRINGER
DOI: 10.1007/s00464-018-6344-4
Keywords
Gastroesophageal reflux disease; Obesity; Body mass index; Sleeve gastrectomy; Asymptomatic diseases; 24-h pH-monitoring
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BackgroundLaparoscopic sleeve gastrectomy (LSG) has become the most frequently performed bariatric procedure to date. However, LSG is known to worsen pre-operative and result in de novo gastroesophageal reflux disease (GERD). Pre-operative evaluation reveals a high percentage of silent GERD of so far unknown influence on post-operative GERD.MethodsProspective data of patients undergoing primary LSG between 01/2012 and 12/2015 were evaluated. Pre-operative GERD-specific evaluation consisted of validated questionnaires, upper endoscopy, 24h-pH-manometry, and esophagograms. Patients were followed-up with questionnaires every 6months, upper endoscopies after 1year and 24h-pH-metry after 2years. Silent GERD was defined as esophagitis grade>B and/or abnormal esophageal acid exposure in absence of symptoms. LSG was performed over a 32F bougie, hiatal hernias>1cm were addressed with posterior hiatoplasty. Excluded were patients with hiatal hernias>4cm, patients with incorrect anatomy (stenosis, fundus too large) and conversion to RYGB for early leaks.Results222 patients were included. Mean follow-up was 3216months, mean preoperative body mass index 49.6 +/- 7.2kg/m(2). 116 patients (52%) presented with post-operative GERD-symptoms, of which 85 (73%) had de novo symptoms. Of those, 48 (of 85, 56%) had no preoperative GERD and 37 (of 85, 44%) silent GERD. 57 patients (26%) had neither pre- nor post-operative GERD, 7 (3%) had silent pre-operative and no postop GERD, and in 19 patients (9%) GERD was cured with LSG. 31 patients (14%) stayed symptomatic. Of 56 patients (25%) with pre-operative silent GERD, 37 (of 54, 66%) became symptomatic.Conclusion LSG leads to a considerable rate of post-operative GERD. De novo-GERD consist of around half of pre-operative silent GERD and completely de novo-GERD. Most patients with pre-operative silent GERD became symptomatic.
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