Journal
SPORTS MEDICINE
Volume 48, Issue 10, Pages 2401-2412Publisher
ADIS INT LTD
DOI: 10.1007/s40279-018-0909-1
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Funding
- National Prevention Research Initiative [G0701877]
- British Heart Foundation
- Cancer Research UK
- Department of Health
- Diabetes UK
- Economic and Social Research Council
- Medical Research Council
- Research and Development Office for the Northern Ireland Health and Social Services
- Chief Scientist Office
- Scottish Executive Health Department
- Stroke Association
- Welsh Assembly Government
- World Cancer Research Fund
- Medical Research Council [MC_UU_12015/3, MC_UU_12015/7]
- Bristol University
- Loughborough University
- Norwegian School of Sport Sciences
- Research Council of Norway [249932/F20]
- Wellcome Trust [102215/2/13/2]
- MRC [MR/K023187/1, MC_UU_12015/7, MC_UU_12015/3, G0701877] Funding Source: UKRI
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IntroductionSedentary time and time spent in various intensity-specific physical activity are co-dependent, and increasing time spent in one behaviour requires decreased time in another.ObjectiveThe aim of the present study was to examine the theoretical associations with reallocating time between categories of intensities and cardiometabolic risk factors in a large and heterogeneous sample of children and adolescents.MethodsWe analysed pooled data from 13 studies comprising 18,200 children and adolescents aged 4-18years from the International Children's Accelerometry Database (ICAD). Waist-mounted accelerometers measured sedentary time, light physical activity (LPA) and moderate-to-vigorous physical activity (MVPA). Cardiometabolic risk factors included waist circumference (WC), systolic blood pressure (SBP), fasting high- and low-density lipoprotein cholesterol (HDL-C and LDL-C), triglycerides, insulin, and glucose. Associations of reallocating time between the various intensity categories with cardiometabolic risk factors were explored using isotemporal substitution modelling.ResultsReplacing 10min of sedentary time with 10min of MVPA showed favourable associations with WC, SBP, LDL-C, insulin, triglycerides, and glucose; the greatest magnitude was observed for insulin (reduction of 2-4%), WC (reduction of 0.5-1%), and triglycerides (1-2%). In addition, replacing 10min of sedentary time with an equal amount of LPA showed beneficial associations with WC, although only in adolescents.ConclusionsReplacing sedentary time and/or LPA with MVPA in children and adolescents is favourably associated with most markers of cardiometabolic risk. Efforts aimed at replacing sedentary time with active behaviours, particularly those of at least moderate intensity, appear to be an effective strategy to reduce cardiometabolic risk in young people.
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