Journal
SMALL
Volume 14, Issue 11, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.201702933
Keywords
micro-/ nanostructures; sensors; transduction; wearable healthcare devices
Categories
Funding
- National Research Foundation, Prime Minister's Office, Singapore, under its Competitive Research Programme Funding Scheme [NRF-CRP13-2014-02]
- National Research Foundation, Prime Minister's Office, Singapore, under its Competitive Research Programme Funding Scheme (CREATE Programme on Nanomaterials for Energy and Water Management)
- China Postdoctoral Science Foundation [2016M592518]
- National Natural Science Fund [61435010, 61575089]
- Science and Technology Planning Project of Guangdong Province [2016B050501005]
- Educational Commission of Guangdong Province [2016KCXTD006]
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Wearable healthcare presents exciting opportunities for continuous, real-time, and noninvasive monitoring of health status. Even though electrochemical and optical sensing have already made great advances, there is still an urgent demand for alternative signal transformation in terms of miniaturization, wearability, conformability, and stretchability. Mechano-based transductive sensing, referred to the efficient transformation of biosignals into measureable mechanical signals, is claimed to exhibit the aforementioned desirable properties, and ultrasensitivity. In this Concept, a focus on pressure, strain, deflection, and swelling transductive principles based on micro-/nanostructures for wearable healthcare is presented. Special attention is paid to biophysical sensors based on pressure/strain, and biochemical sensors based on microfluidic pressure, microcantilever, and photonic crystals. There are still many challenges to be confronted in terms of sample collection, miniaturization, and wireless data readout. With continuing efforts toward solving those problems, it is anticipated that mechano-based transduction will provide an accessible route for multimode wearable healthcare systems integrated with physical, electrophysiological, and biochemical sensors.
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