Journal
SEPARATION SCIENCE AND TECHNOLOGY
Volume 53, Issue 16, Pages 2671-2682Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/01496395.2018.1461113
Keywords
Anticancer drug; cobalt-substituted magnetite; flutamide; heterogeneous Fenton; wastewater
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Nano-sized cobalt-substituted magnetite has been synthesized and used as a heterogeneous Fenton catalyst for the removal of anticancer drug Flutamide (FLU) from a solution with a concentration of 150 mu M. By using response surface methodology at the optimal conditions of Fenton oxidation (FO) process, 67.7% FLU removal was obtained. In order to increase the removal efficiency of the drug, ozonation was applied in combination with FO process. Maximum FLU removal (93.0%) was obtained using 0.6 g O3 l(-1)h(-1) and 163 mg L-1 of the catalyst. The results indicate that the proposed method is efficient for the degradation of cytotoxic drugs.
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