Metallic nickel nitride nanosheet: An efficient catalyst electrode for sensitive and selective non-enzymatic glucose sensing

It is significantly important to design enzyme-free electrocatalyst for sensitive and selective detection of glucose (Glu). In this paper, we report that metallic nickel nitride nanosheet on Ti mesh (Ni3N NS/Ti) behaves as an efficient three-dimensional catalyst electrode for Glu electro-oxidation under alkaline conditions. We further demonstrate the use of such Ni3N NS/Ti as a non-enzymatic electrochemical Glu sensor superior in analytical performances. The introduction of the Ni3N NS/Ti can provide a high surface area and lead to high sensitivity to Glu. This sensor shows a fast amperometric response toward Glu and can achieve steady state current density within 5 s, a detection range of 0.2 mu M-1.5 mM, a detection limit of 0.06 mu M (S/N =3), a response sensitivity of 7688 mu AmM-1 cm(-2), and satisfactory selectivity and reproducibility. In addition, it also works effectively for Glu detection in human blood serum, promising its application toward determination of Glu in real samples. (C) 2017 Elsevier B.V. All rights reserved.