Pillar[6]arene/acridine orange host-guest complexes as colorimetric and fluorescence sensors for choline compounds and further application in monitoring enzymatic reactions

A novel pillararene-indicator system between anionic water-soluble pillar[6] arene (WP6) and an aromatic fluorescent dye acridine orange (AO) was constructed. Upon complexation with electron-rich cavity of WP6, AO showed a fluorescence quenching and color change due to the host-guest charge-transfer interactions. The established pillararene-indicator system was further employed in the detection of choline compounds and monitoring enzymatic reactions. (C) 2017 Elsevier B.V. All rights reserved.