Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 255, Issue -, Pages 384-390Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2017.08.030
Keywords
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Funding
- National Research Foundation of Korea [NRF-2017M3A9F1033056]
- Korea Evaluation Institution of Industrial Tehnology [10077474]
- basic research program of ETRI [12RC1510]
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In spite of the invasiveness and pain related with it, blood sampling is necessary in point-of-care systems to obtain biochemical information. In this context, a substitute micro-scale needle for minimally invasive and painless blood sampling has been developed. In conventional microneedle fabrication methods, it is difficult to combine the features of a sharp tip shape, appropriate length, and a hollow structure simultaneously. Thus, here we report a sharp, hollow, and ultrahigh aspect ratio microneedle long enough to get to the blood vessels which is capable of minimizing the pain caused by nerve pricking. It is equipped with a fluidic system to handle blood. The structure of the microneedle was precisely formed using a drawing lithography method and a sharp angle tip was formed using a laser-cutting method. (C) 2017 Elsevier B.V. All rights reserved.
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