Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 263, Issue -, Pages 661-667Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2018.02.154
Keywords
Artificial fluorescent protein; Fluorescent recognition; Relay sensing; Silver ion; Nanosensor
Funding
- NSFC [21676047, 21421005, 21406028]
- Doctoral Scientific Fund [20130041120014]
- Fundamental Research Funds for the Central Universities [DUT14ZD214]
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Green fluorescent protein (GFP) becomes one of the most important imaging tools in biology and biomedicine. To simplify usage, expand the application and avoid complicated operations, a kind of artificial fluorescent protein (AFP) is inspired and fabricated by lighting up human serum albumin (HSA) with loading microenvironment-sensitive fluorescent dye DMAR, which could be applied in HSA assay in human urine and serum samples as a physiological indicator of diagnosis in clinical. Besides, the AFP, DMAR/HSA, could act as a nanosensor for Ag+ sensing with good selectivity by a new relay recognition strategy. (C) 2018 Elsevier B.V. All rights reserved.
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